Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23132028 | 0.83 | BRD4 (0.35) | PPARGBRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL21390681 | 0.80 | BRD4 (0.35) | PPARGBRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL21391052 | 0.77 | ACSS2 (0.36) | PPARGBRD4PLA2G10PLA2G2A | |
| SCHEMBL18791656 | 0.76 | BRD4 (0.44) | PPARGBRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL21390928 | 0.76 | HPGDS (0.36) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL21390877 | 0.74 | CSNK1D (0.36) | PPARGPDE10APDE2A | |
| SCHEMBL21390751 | 0.73 | CCR9 (0.32) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21391161 | 0.72 | HDAC3 (0.30) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21391045 | 0.71 | ACLY (0.30) | — | |
| SCHEMBL21391160 | 0.71 | ACSS2 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |