Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391134 | 0.89 | RORC (0.33) | RORCPARP1 | |
| SCHEMBL21391143 | 0.85 | MAT2A (0.32) | PDE2APDE10ACYP11B1CYP11B2TRPV1 | |
| SCHEMBL21391136 | 0.84 | CYP11B1 (0.34) | RORCCYP11B1CYP11B2TRPV1 | |
| SCHEMBL21391141 | 0.84 | RORC (0.32) | RORC | |
| SCHEMBL21390903 | 0.83 | RORC (0.32) | RORCPDE2A | |
| SCHEMBL21391133 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL21390907 | 0.83 | RORC (0.32) | RORCPDE2A | |
| SCHEMBL21390955 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL21390916 | 0.82 | RORC (0.32) | RORC | |
| SCHEMBL21390990 | 0.82 | RORC (0.32) | RORCCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |