Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391160 | 0.82 | ACSS2 (0.38) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL18791986 | 0.74 | ACSS2 (0.33) | — | |
| SCHEMBL21391167 | 0.72 | PPARG (0.40) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21391173 | 0.72 | ACSS2 (0.36) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL23132028 | 0.71 | BRD4 (0.35) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21390877 | 0.69 | CSNK1D (0.36) | — | |
| SCHEMBL23132027 | 0.67 | ACSS2 (0.34) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21390681 | 0.67 | BRD4 (0.35) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21391045 | 0.67 | ACLY (0.30) | — | |
| SCHEMBL21390936 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |