Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | FABP2 | P12104 | 1/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378829 | 0.89 | PPARG (0.74) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL822492 | 0.85 | PPARA (0.77) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL9588829 | 0.81 | HSD11B1 (0.49) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL21391273 | 0.80 | SMN1; SMN2 (0.51) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL8406665 | 0.79 | HPGD (0.69) | MEN1MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11377777 | 0.79 | PPARG (0.58) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL3677325 | 0.79 | SRD5A2 (0.53) | HPGDATMTDP1PARP1ALOX15 | |
| SCHEMBL3445668 | 0.78 | PARP1 (0.63) | MAPK1ATMTDP1VNN1PARP1 | |
| SCHEMBL11433076 | 0.78 | TSHR (0.48) | PPARAPPARGFABP2SLC22A12CYP2C19 | |
| SCHEMBL135713 | 0.77 | PPARA (0.72) | PPARAPPARGFABP2SLC22A12CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | LIPC, CYP27A1, HSD17B10 | PPARA 14/4885PPARG 32/4885FABP2 164/4885 |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | LIPC, CYP27A1, HSD17B10 | PPARA 14/4885PPARG 32/4885FABP2 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.