Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15417948 | 0.88 | MTNR1B (0.55) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL15338464 | 0.87 | MAOB (0.55) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL10664626 | 0.87 | MAOB (0.57) | MAOBELANEMRGPRX4SMN1; SMN2NPC1 | |
| SCHEMBL8318002 | 0.86 | PTGER1 (0.73) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8675320 | 0.86 | MRGPRX4 (0.54) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8678298 | 0.85 | PTGER1 (0.58) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL7543730 | 0.85 | MAOB (0.52) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8678301 | 0.84 | MTNR1B (0.50) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8321075 | 0.84 | MTNR1B (0.60) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8325723 | 0.83 | PTGER1 (0.59) | PTGER1PTGER4PTGER3PTGER2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | LIPC, CYP27A1, HSD17B10 | PTGER1 1515/4885PTGER4 1861/4885PTGER3 2139/4885 |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | LIPC, CYP27A1, HSD17B10 | PTGER1 1515/4885PTGER4 1861/4885PTGER3 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.