Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338464 | 0.88 | MAOB (0.55) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL7543730 | 0.86 | MAOB (0.52) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL21391358 | 0.86 | PTGER1 (0.54) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL10664626 | 0.85 | MAOB (0.57) | MRGPRX4MAOBSMN1; SMN2NPC1HPGD | |
| SCHEMBL11179076 | 0.84 | MAOB (0.56) | MRGPRX4MAOBSMN1; SMN2NPC1HPGD | |
| SCHEMBL21483708 | 0.84 | MAOB (0.56) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL15417948 | 0.84 | MTNR1B (0.55) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL9528336 | 0.83 | MRGPRX4 (0.53) | MRGPRX4MAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL21483714 | 0.83 | ALDH1A1 (0.55) | MRGPRX4MAOBSMN1; SMN2NPC1HPGD | |
| SCHEMBL8318002 | 0.83 | PTGER1 (0.73) | MRGPRX4MAOBPTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |