Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | OTC | P00480 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947948 | 0.84 | KMT2A (0.41) | MEN1KMT2AALDH1A1OTCSMN1; SMN2 | |
| SCHEMBL21391388 | 0.79 | MEN1 (0.42) | MEN1KMT2AALDH1A1OTCSMN1; SMN2 | |
| SCHEMBL7936587 | 0.78 | KMT2A (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2DPP7 | |
| SCHEMBL16853212 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2PAOX | |
| SCHEMBL12660515 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2PAOX | |
| SCHEMBL7944266 | 0.75 | ANPEP (0.52) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL20813199 | 0.74 | HPGD (0.54) | ALDH1A1CASP2HPGDTSHR | |
| SCHEMBL24611784 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2PAOX | |
| SCHEMBL14198854 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2PAOX | |
| SCHEMBL13043221 | 0.73 | OTC (0.65) | KMT2AOTCDPP7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210078983-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | Cellix Bio Provate Limited (IN) | 2021-03-18 | — | — | US | disclosed |
| US-10858349-B2 | Compositions and methods for the treatment of cancer | CELLIX BIO PRIVATE LIMITED (IN) | 2020-12-08 | — | — | US | disclosed |
| US-20190292171-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | CELLIX BIO PRIVATE LIMITED (IN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078983-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885ALDH1A1 2768/4885 |
| US-20190292171-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885ALDH1A1 2768/4885 |
| US-10858349-B2 | Compositions and methods for the treatment of cancer | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885ALDH1A1 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.