Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829056 | 0.85 | MEN1 (0.61) | MEN1KMT2AALDH1A1CASP2NAAA | |
| SCHEMBL7947948 | 0.82 | KMT2A (0.41) | MEN1KMT2ADPP7ALDH1A1RRM1 | |
| SCHEMBL5210948 | 0.81 | MEN1 (0.42) | MEN1KMT2ADPP7ALDH1A1CASP2 | |
| SCHEMBL23710264 | 0.81 | DPP7 (0.38) | MEN1KMT2ADPP7RRM1GNAI3 | |
| SCHEMBL13056218 | 0.81 | DPP7 (0.38) | MEN1KMT2ADPP7RRM1GNAI3 | |
| SCHEMBL18756720 | 0.80 | CASP2 (0.52) | ALDH1A1CASP2NAAASLC6A5 | |
| SCHEMBL22509626 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1CASP2NAAA | |
| SCHEMBL21391368 | 0.79 | MEN1 (0.39) | MEN1KMT2ADPP7ALDH1A1RRM1 | |
| SCHEMBL23733329 | 0.79 | TSHR (0.41) | MEN1KMT2AALDH1A1CASP2SMN1; SMN2 | |
| SCHEMBL5211823 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CASP2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210078983-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | Cellix Bio Provate Limited (IN) | 2021-03-18 | — | — | US | disclosed |
| US-10858349-B2 | Compositions and methods for the treatment of cancer | CELLIX BIO PRIVATE LIMITED (IN) | 2020-12-08 | — | — | US | disclosed |
| US-20190292171-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | CELLIX BIO PRIVATE LIMITED (IN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078983-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885DPP7 3913/4885 |
| US-20190292171-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885DPP7 3913/4885 |
| US-10858349-B2 | Compositions and methods for the treatment of cancer | SI, HBG2, HBG1 | MEN1 999/4885KMT2A 4424/4885DPP7 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.