SCHEMBL21391540

SCHEMBL21391540

O=C(C[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)C1CC1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.49
LGALS3 P17931 3/20 0.49
LGALS4 P56470 3/20 0.49
IGF2R P11717 2/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
AMY1A P0DUB6 1/20 0.44
PTPN1 P18031 1/20 0.43
GJA1 P17302 1/20 0.43
GJB2 P29033 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TYR P14679 2/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391500 1.00 LGALS8 (0.49) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL21391437 1.00 LGALS8 (0.49) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL21391502 1.00 LGALS8 (0.49) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL20161431 0.85 IGF2R (0.55) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL13515800 0.83 LGALS8 (0.64) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL17468102 0.83 LGALS8 (0.64) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL12756242 0.83 LGALS8 (0.64) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL21391458 0.82 LGALS3 (0.52) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL22906100 0.82 LGALS3 (0.52) LGALS8LGALS3LGALS4IGF2RMEN1
SCHEMBL21391506 0.82 LGALS3 (0.52) LGALS8LGALS3LGALS4IGF2RMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210017211-A1 OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2021-01-21 US disclosed
WO-2019182087-A1 OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2019-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017211-A1 OLIGOSACCHARIDE C-GLYCOSIDE DERIVATIVES OSTC, FUT6, FUT5 LGALS8 253/4885LGALS3 188/4885LGALS4 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.