SCHEMBL21391591

SCHEMBL21391591

O=C=NCCCc1cccc(N=C=O)c1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MIF P14174 5/20 0.41
CYP3A4 P08684 3/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NAAA Q02083 3/20 0.36
NOS1 P29475 2/20 0.34
TRPA1 O75762 1/20 0.34
CYP1A2 P05177 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HTR3A P46098 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9178534 0.90 MIF (0.42) MIFCYP3A4TSHRMAPK1TDP1
SCHEMBL9752705 0.86 MIF (0.48) MIFNAAANOS1TRPA1HTR3A
SCHEMBL16163537 0.84 MAPK1 (0.41) MIFCYP3A4TSHRMAPK1TDP1
SCHEMBL6805641 0.84 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1NOS1
SCHEMBL9799010 0.83 SIGMAR1 (0.41) MIFCYP3A4TSHRMAPK1TDP1
SCHEMBL11608082 0.82 LPL (0.41) CYP3A4TSHRNOS1TRPA1GABRA1
SCHEMBL6808470 0.81 MIF (0.50) MIFNAAANOS1HTR3AHTR3E
SCHEMBL27320613 0.81 LPL (0.47) TDP1GABRA1GABRB2
SCHEMBL21248287 0.80 HTR3E (0.51) MIFHTR3AHTR3EHTR3BHTR3D
SCHEMBL5495096 0.80 CYP4F2 (0.44) CYP3A4TSHRMAPK1TDP1NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182071-A1 LIQUID CRYSTAL ALIGNMENT AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed