SCHEMBL21392005

SCHEMBL21392005

Cc1ccc(N(c2ccc(CC(C)(C)C)cc2)c2ccc(CC(C)(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
CYP2C19 P33261 1/20 0.38
IDO1 P14902 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.37
CNR2 P34972 3/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
CNR1 P21554 1/20 0.35
AGXT P21549 2/20 0.34
ACHE P22303 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20059295 0.93 CYP2C19 (0.46) ESR1ALDH1A1CYP2C19CNR2CYP1A2
SCHEMBL19649024 0.88 CYP2C19 (0.42) ESR1ALDH1A1CYP2C19CNR2CYP1A2
SCHEMBL394340 0.87 ESR1 (0.61) ESR1TSHRIDO1THRATHRB
SCHEMBL20386561 0.83 ALDH1A1 (0.50) ESR1ALDH1A1TSHRCYP2C19THRA
SCHEMBL21215243 0.80 HSD11B1 (0.45) ALDH1A1CYP2C19CNR2
SCHEMBL12238163 0.79 ESR1 (0.35) ESR1CYP2C19CNR2CNR1
SCHEMBL18925248 0.78 CYP2C19 (0.43) ALDH1A1CYP2C19CNR2CYP1A2TAAR1
SCHEMBL13383799 0.78 TSHR (0.46) ALDH1A1TSHRCYP2C19IDO1CNR2
SCHEMBL12203011 0.78 CYP1A2 (0.52) ALDH1A1TSHRCYP2C19IDO1CNR2
SCHEMBL1334409 0.78 ALDH1A1 (0.54) ALDH1A1TSHRCYP2C19IDO1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11094474-B2 Photoelectric conversion element, dye-sensitized solar cell, metal complex dye, dye composition, and oxide semiconductor electrode FUJIFILM CORPORATION (JP) 2021-08-17 US disclosed
US-20190295779-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE COMPOSITION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM CORPORATION (JP) 2019-09-26 US disclosed