Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688813 | 0.84 | DGAT1 (0.38) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL241533 | 0.80 | DGAT1 (0.46) | DGAT1CA2CA1CA7CYP2D6 | |
| Methyl Alcohol SCHEMBL27995686 | 0.78 | DGAT1 (0.44) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL14957644 | 0.77 | CA2 (0.38) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL1246384 | 0.77 | CTSD (0.39) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL28452577 | 0.76 | CAPN1 (0.39) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL28316203 | 0.75 | DGAT1 (0.42) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL2648388 | 0.75 | DGAT1 (0.42) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL332199 | 0.73 | GAA (0.48) | DGAT1CA2CA1CA7CYP2D6 | |
| SCHEMBL82881 | 0.73 | GAA (0.55) | DGAT1CA2CA1CA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |