SCHEMBL21392431

SCHEMBL21392431

CCc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3cccc4c3oc3ccccc34)c3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
PSMD14 O00487 1/20 0.39
RECQL P46063 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
ALOX5 P09917 1/20 0.37
PDE10A Q9Y233 5/20 0.35
RAB9A P51151 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
PRKDC P78527 1/20 0.33
EDNRA P25101 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392432 0.89 POLB (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL21392456 0.89 MAPK1 (0.47) POLBL3MBTL1ALDH1A1SMN1; SMN2MEN1
SCHEMBL26345603 0.88 POLB (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL21392557 0.86 ESR1 (0.49) RECQLALDH1A1MEN1KMT2AKDM4E
SCHEMBL15394041 0.85 RECQL (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL22707307 0.85 ALDH1A1 (0.38) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL21392592 0.85 PDE10A (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL15394504 0.85 L3MBTL1 (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL15393986 0.85 RECQL (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1
SCHEMBL21392653 0.85 RECQL (0.41) POLBPSMD14RECQLL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 POLB 2385/4885PSMD14 1482/4885RECQL 2992/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 POLB 2385/4885PSMD14 1482/4885RECQL 2992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.