SCHEMBL21392494

SCHEMBL21392494

CC1(C)c2ccccc2-c2ccc(N(c3ccc4c(c3)oc3ccccc34)c3cc4c(cc3-c3ccccc3)-c3ccccc3C4(C)C)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALK Q9UM73 5/20 0.32
AHR P35869 1/20 0.32
PGR P06401 2/20 0.32
MAOA P21397 2/20 0.30
PDK2 Q15119 1/20 0.30
CA12 O43570 1/20 0.30
ALDH2 P05091 1/20 0.30
AKR1B1 P15121 1/20 0.30
MAOB P27338 1/20 0.30
HSD17B3 P37058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392493 0.96 MEN1 (0.32) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL26999819 0.94 KDM4E (0.35) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL21392495 0.93 ALK (0.31) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL21392490 0.90 MEN1 (0.35) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL27281000 0.90 PGR (0.34) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL27049720 0.90 PGR (0.32) MEN1KMT2ATHRBRECQLBLM
SCHEMBL21392580 0.90 ALK (0.33) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL21392639 0.90 PLA2G2A (0.34) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL22517328 0.90 MEN1 (0.32) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL22567911 0.90 MEN1 (0.32) MEN1KMT2AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 MEN1 1414/4885KMT2A 1198/4885MAPT 665/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 MEN1 1414/4885KMT2A 1198/4885MAPT 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.