Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 2/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195419 | 0.81 | HSD17B10 (0.58) | HSD17B10KDM4ELMNAOPRM1OPRK1 | |
| SCHEMBL21392838 | 0.80 | ROCK2 (0.52) | HSD17B10KDM4ELMNAOPRM1OPRK1 | |
| SCHEMBL17142324 | 0.78 | HSD17B10 (0.64) | HSD17B10LMNAOPRM1OPRK1SCD5 | |
| SCHEMBL29585212 | 0.78 | HSD17B10 (0.55) | HSD17B10KDM4ELMNAOPRM1OPRK1 | |
| SCHEMBL7729871 | 0.77 | TSHR (0.66) | HSD17B10LMNAKMT2AMEN1SCD5 | |
| SCHEMBL21392963 | 0.77 | ALDH1A1 (0.48) | HSD17B10KDM4ELMNAALDH1A1SCD | |
| SCHEMBL17024860 | 0.74 | KMT2A (0.71) | LMNAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL17024862 | 0.74 | KMT2A (0.71) | LMNAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL21393226 | 0.74 | HSD17B10 (0.59) | HSD17B10OPRM1OPRK1SCD5ALDH1A1 | |
| SCHEMBL17151071 | 0.74 | HSD17B10 (0.59) | HSD17B10KDM4EOPRM1OPRK1SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | HSD17B10 2792/4885KDM4E 3016/4885LMNA 1016/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | HSD17B10 3600/4885KDM4E 210/4885LMNA 3321/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | HSD17B10 2792/4885KDM4E 3016/4885LMNA 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.