Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23679567 | 0.88 | KDM4E (0.59) | KDM4ETAS1R3TAS1R1POLBPOLA1 | |
| SCHEMBL20154878 | 0.87 | KDM4E (0.71) | KDM4ETAS1R3TAS1R1POLBPOLA1 | |
| SCHEMBL18521398 | 0.87 | KDM4E (0.71) | KDM4ETAS1R3TAS1R1POLBPOLA1 | |
| SCHEMBL26197044 | 0.87 | KDM4E (0.71) | KDM4ETAS1R3TAS1R1POLBPOLA1 | |
| SCHEMBL21393001 | 0.86 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1POLBPOLA1 | |
| SCHEMBL20325348 | 0.83 | POLB (0.64) | TAS1R3TAS1R1POLBIMPDH2P2RY2 | |
| SCHEMBL20325346 | 0.83 | POLB (0.64) | TAS1R3TAS1R1POLBIMPDH2P2RY2 | |
| SCHEMBL20225058 | 0.81 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1POLBIMPDH2 | |
| SCHEMBL22990582 | 0.81 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1POLBIMPDH2 | |
| SCHEMBL20434918 | 0.81 | KDM4E (0.57) | KDM4ETAS1R3TAS1R1POLBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |