Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666972 | 0.71 | SMN1; SMN2 (0.36) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL21393781 | 0.64 | KDM4E (0.30) | — | |
| SCHEMBL31667098 | 0.62 | BRPF1 (0.34) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL13376898 | 0.60 | BRPF1 (0.33) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL21620866 | 0.59 | BRPF1 (0.35) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL13560811 | 0.58 | BRPF1 (0.58) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL17821042 | 0.57 | TRIM24 (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL21393358 | 0.57 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL21393396 | 0.57 | — | — | |
| SCHEMBL17950685 | 0.55 | LMNA (0.55) | CA12CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |