Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632874 | 0.79 | LMNA (0.39) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL20203156 | 0.72 | CCR1 (0.32) | — | |
| SCHEMBL11115133 | 0.69 | KDR (0.35) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL13946887 | 0.69 | ALDH1A1 (0.34) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL30895748 | 0.65 | PDXK (0.39) | — | |
| SCHEMBL21393347 | 0.64 | — | — | |
| SCHEMBL21393778 | 0.64 | MEN1 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL31526243 | 0.63 | ADORA2A (0.42) | KDM4EALDH1A1LMNA | |
| SCHEMBL21393679 | 0.60 | BRD4 (0.37) | — | |
| SCHEMBL305898 | 0.60 | CCR1 (0.39) | KDM4EMEN1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |