Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203156 | 0.78 | CCR1 (0.32) | — | |
| SCHEMBL304349 | 0.76 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL30255032 | 0.76 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL15240397 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL5212066 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL25195292 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL29956118 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL30356708 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL3649684 | 0.71 | ALDH1A1 (0.46) | MEN1ALDH1A1KMT2ATDP1DAO | |
| SCHEMBL29952613 | 0.71 | ALDH1A1 (0.46) | MEN1ALDH1A1KMT2ATDP1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |