Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.34 |
| ▸ | NOS2 | P35228 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863142 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL304349 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL30255032 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL19489657 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EMAPTNOS3NOS2 | |
| SCHEMBL8131114 | 0.78 | NOS2 (0.37) | ALDH1A1MEN1KMT2ATDP1NOS3 | |
| SCHEMBL27776287 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL25195292 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL30356708 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL5212066 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL29956118 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |