Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393598 | 0.85 | PDE7A (0.30) | — | |
| SCHEMBL21393820 | 0.82 | GAA (0.30) | — | |
| SCHEMBL21393786 | 0.81 | POLB (0.31) | KDM4EALDH1A1POLB | |
| SCHEMBL21393793 | 0.67 | — | — | |
| SCHEMBL21393791 | 0.64 | GAA (0.30) | — | |
| SCHEMBL21393891 | 0.58 | — | — | |
| SCHEMBL21363536 | 0.57 | TRPA1 (0.44) | KDM4EPOLBLMNAHTT | |
| SCHEMBL21393579 | 0.57 | LMNA (0.44) | KDM4EPOLBLMNAHTTTRIM33 | |
| SCHEMBL25165800 | 0.56 | TRPA1 (0.48) | KDM4EPOLBLMNAHTT | |
| SCHEMBL21393696 | 0.55 | KDM4E (0.36) | KDM4EALDH1A1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |