Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 10/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.44 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384576 | 0.91 | MRGPRX1 (0.63) | MRGPRX1TSPOSMOCA12CA1 | |
| SCHEMBL21394554 | 0.87 | MRGPRX1 (0.49) | MRGPRX1TSPOSMOCCKBRCA12 | |
| SCHEMBL21394560 | 0.86 | MRGPRX1 (0.51) | MRGPRX1TSPOSMOCA12CA1 | |
| SCHEMBL21394361 | 0.86 | MRGPRX1 (0.58) | MRGPRX1TSPOKDM1ASMOCA12 | |
| SCHEMBL21394415 | 0.84 | MRGPRX1 (0.61) | MRGPRX1TSPOSLC10A6HRH1TMPRSS4 | |
| SCHEMBL21394420 | 0.84 | MRGPRX1 (0.56) | MRGPRX1TSPOSMOCA12CA1 | |
| SCHEMBL21381353 | 0.81 | MRGPRX1 (0.62) | MRGPRX1TSPOHRH1LMNATMPRSS4 | |
| SCHEMBL21394555 | 0.81 | MRGPRX1 (0.49) | MRGPRX1TSPOHRH1TMPRSS4TRPV1 | |
| SCHEMBL331420 | 0.79 | TMPRSS4 (0.63) | CA12CA1CA2CA9HTT | |
| SCHEMBL30771730 | 0.79 | TMPRSS4 (0.63) | CA12CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |