Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 10/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394560 | 0.91 | MRGPRX1 (0.51) | MRGPRX1TMPRSS4TRPV1TSPOHRH1 | |
| SCHEMBL21394554 | 0.89 | MRGPRX1 (0.49) | MRGPRX1TMPRSS4TRPV1TSPOHRH1 | |
| SCHEMBL21394415 | 0.88 | MRGPRX1 (0.61) | MRGPRX1TMPRSS4TSPOHRH1 | |
| SCHEMBL21394417 | 0.81 | MRGPRX1 (0.53) | MRGPRX1TMPRSS4TRPV1TSPOHRH1 | |
| SCHEMBL21381353 | 0.81 | MRGPRX1 (0.62) | MRGPRX1TMPRSS4TRPV1TSPOHRH1 | |
| SCHEMBL21384576 | 0.80 | MRGPRX1 (0.63) | MRGPRX1TMPRSS4TSPOHRH1 | |
| SCHEMBL21394420 | 0.79 | MRGPRX1 (0.56) | MRGPRX1TMPRSS4TRPV1TSPOHRH1 | |
| SCHEMBL25354031 | 0.79 | TMPRSS4 (0.58) | TMPRSS4TRPV1MAPTMEN1TSHR | |
| SCHEMBL21394361 | 0.75 | MRGPRX1 (0.58) | MRGPRX1TMPRSS4TSPOMAPT | |
| SCHEMBL21384571 | 0.75 | MRGPRX1 (0.60) | MRGPRX1TMPRSS4TSPOHRH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |