Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 10/20 | 0.56 |
| ▸ | TSPO | P30536 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394560 | 0.88 | MRGPRX1 (0.51) | MRGPRX1TSPOHRH1SMOTMPRSS4 | |
| SCHEMBL21384576 | 0.86 | MRGPRX1 (0.63) | MRGPRX1TSPOHRH1SMOTMPRSS4 | |
| SCHEMBL21394554 | 0.85 | MRGPRX1 (0.49) | MRGPRX1TSPOHRH1SMOTMPRSS4 | |
| SCHEMBL21394417 | 0.84 | MRGPRX1 (0.53) | MRGPRX1TSPOHRH1SMOTMPRSS4 | |
| SCHEMBL21394361 | 0.82 | MRGPRX1 (0.58) | MRGPRX1TSPOSMOTMPRSS4CA12 | |
| SCHEMBL21394555 | 0.79 | MRGPRX1 (0.49) | MRGPRX1TSPOHRH1TMPRSS4TRPV1 | |
| SCHEMBL21381353 | 0.79 | MRGPRX1 (0.62) | MRGPRX1TSPOHRH1TMPRSS4TRPV1 | |
| SCHEMBL21394415 | 0.76 | MRGPRX1 (0.61) | MRGPRX1TSPOHRH1TMPRSS4 | |
| SCHEMBL20206206 | 0.76 | TMPRSS4 (0.65) | ALOX15TMPRSS4TRPV1CA12CA1 | |
| SCHEMBL15847536 | 0.74 | MRGPRX1 (0.59) | MRGPRX1TSPOHRH1AVPR2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |