Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353830 | 1.00 | NPC1 (0.37) | NPC1TSHRRAB9ASMN1; SMN2NPY5R | |
| SCHEMBL21384487 | 0.88 | ABCC8 (0.43) | NPC1TSHRRAB9ASMN1; SMN2NPY5R | |
| SCHEMBL29356900 | 0.88 | KCNJ6 (0.42) | NPC1TSHRRAB9ASMN1; SMN2NPY5R | |
| SCHEMBL29353780 | 0.88 | ABCC8 (0.43) | NPC1TSHRRAB9ASMN1; SMN2NPY5R | |
| SCHEMBL21394975 | 0.88 | KCNJ6 (0.42) | NPC1TSHRRAB9ASMN1; SMN2NPY5R | |
| SCHEMBL21394766 | 0.87 | ALDH1A1 (0.39) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29357041 | 0.85 | L3MBTL1 (0.46) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394626 | 0.85 | L3MBTL1 (0.46) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394503 | 0.85 | ABCC8 (0.42) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394572 | 0.79 | TSHR (0.44) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |