Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384487 | 0.90 | ABCC8 (0.43) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL29353780 | 0.90 | ABCC8 (0.43) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL21394975 | 0.88 | KCNJ6 (0.42) | NPC1RAB9ATSHRSMN1; SMN2F10 | |
| SCHEMBL29356900 | 0.88 | KCNJ6 (0.42) | NPC1RAB9ATSHRSMN1; SMN2F10 | |
| SCHEMBL29353830 | 0.87 | NPC1 (0.37) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL21394620 | 0.87 | NPC1 (0.37) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL21394503 | 0.86 | ABCC8 (0.42) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL29354586 | 0.84 | L3MBTL1 (0.47) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL21394760 | 0.84 | L3MBTL1 (0.47) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL21394481 | 0.83 | RAB9A (0.46) | ALDH1A1NPC1RAB9ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |