Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394604 | 0.90 | RAB9A (0.43) | RAB9AHIF1AEPAS1DEGS1PARP1 | |
| SCHEMBL29358522 | 0.90 | RAB9A (0.43) | RAB9AHIF1AEPAS1DEGS1PARP1 | |
| SCHEMBL21394774 | 0.89 | PTGS1 (0.42) | RAB9AGPR52PTGS1 | |
| SCHEMBL21394664 | 0.88 | RAB9A (0.44) | RAB9ACYP11B1CYP11B2DYRK1APARP1 | |
| SCHEMBL21394661 | 0.87 | CYP11B1 (0.52) | RAB9ACYP11B1CYP11B2PARP1CSF1R | |
| SCHEMBL21394597 | 0.86 | RAB9A (0.44) | RAB9ACYP11B1CYP11B2GPR52PARP1 | |
| SCHEMBL21384513 | 0.85 | RAB9A (0.42) | RAB9AGPR52HIF1AEPAS1DYRK1A | |
| SCHEMBL21395043 | 0.83 | RAB9A (0.47) | RAB9AGPR52PARP1CSF1R | |
| SCHEMBL29355445 | 0.83 | RAB9A (0.47) | RAB9AGPR52PARP1CSF1R | |
| SCHEMBL21394770 | 0.83 | RAB9A (0.46) | RAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |