Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394704 | 0.89 | CACNA1H (0.37) | AHRKDM4ENPC1RAB9ADEGS1 | |
| SCHEMBL21394991 | 0.82 | AHR (0.42) | AHRABCB1ABCC1NPY5RKDM4E | |
| SCHEMBL21394956 | 0.77 | AHR (0.44) | AHRABCB1ABCC1KDM4ENPC1 | |
| SCHEMBL21394572 | 0.76 | TSHR (0.44) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL21394958 | 0.76 | P2RX3 (0.42) | AHRABCB1ABCC1KDM4EGCK | |
| SCHEMBL29356925 | 0.76 | GCK (0.44) | ABCB1ABCC1KDM4EGCKNPC1 | |
| SCHEMBL21394784 | 0.76 | GCK (0.44) | ABCB1ABCC1KDM4EGCKNPC1 | |
| SCHEMBL21394747 | 0.76 | AHR (0.38) | AHRABCB1ABCC1KDM4EGCK | |
| SCHEMBL29357109 | 0.76 | TSHR (0.44) | KDM4ENPC1RAB9AMEN1KMT2A | |
| SCHEMBL21394981 | 0.75 | SMN1; SMN2 (0.53) | ABCB1ABCC1KDM4EDEGS1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |