Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394921 | 0.91 | NPC1 (0.48) | P2RX3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL21394655 | 0.91 | CYP3A4 (0.40) | P2RX3GCKDEGS1 | |
| SCHEMBL21394649 | 0.88 | P2RX3 (0.45) | P2RX3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL21395123 | 0.86 | P2RX3 (0.43) | P2RX3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29356925 | 0.85 | GCK (0.44) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21394784 | 0.85 | GCK (0.44) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21395084 | 0.84 | AHR (0.39) | KDM4ENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL21395156 | 0.81 | KDM4E (0.42) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21394747 | 0.81 | AHR (0.38) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21394981 | 0.81 | SMN1; SMN2 (0.53) | KDM4EALDH1A1SMN1; SMN2ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |