Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394396 | 0.85 | KCNQ3 (0.47) | GCKKDM4EALDH1A1DEGS1KCNQ3 | |
| SCHEMBL21395030 | 0.84 | NPC1 (0.45) | GCKKDM4EABCB1ABCC1NPC1 | |
| SCHEMBL21394698 | 0.81 | GCK (0.41) | GCKKDM4EABCB1ABCC1NPC1 | |
| SCHEMBL21394932 | 0.81 | CHEK1 (0.42) | CHEK1 | |
| SCHEMBL21394694 | 0.80 | GCK (0.42) | GCKKDM4EABCB1ABCC1NPC1 | |
| SCHEMBL21394726 | 0.80 | RAB9A (0.42) | GCKNPC1ALDH1A1PKMTSHR | |
| SCHEMBL21394654 | 0.80 | WNT3A (0.44) | GCKKDM4EABCB1ABCC1NPC1 | |
| SCHEMBL21394952 | 0.80 | KCNQ3 (0.44) | GCKCYP3A4SIRT2DEGS1KCNQ3 | |
| SCHEMBL21395023 | 0.80 | DEGS1 (0.40) | CYP3A4SIRT2DEGS1 | |
| SCHEMBL21395009 | 0.78 | PARP1 (0.53) | KDM4EABCB1ABCC1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |