Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394643 | 0.89 | KDM4E (0.44) | KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21394726 | 0.86 | RAB9A (0.42) | KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21395030 | 0.83 | NPC1 (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21394395 | 0.82 | KDM4E (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21395009 | 0.81 | PARP1 (0.53) | KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21394393 | 0.80 | NPC1 (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21394947 | 0.79 | JUN (0.43) | KMT2ARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21394654 | 0.79 | WNT3A (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21394698 | 0.78 | GCK (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL21394642 | 0.78 | GCK (0.48) | RAB9AALDH1A1CXCR2KDM4EGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |