Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395023 | 0.88 | DEGS1 (0.40) | SIRT2CYP3A4DEGS1 | |
| SCHEMBL21395154 | 0.82 | TMPRSS4 (0.44) | SIRT2TMPRSS4F10CYP3A4DEGS1 | |
| SCHEMBL21395150 | 0.81 | TMPRSS4 (0.43) | SIRT2TMPRSS4F10CYP3A4DEGS1 | |
| SCHEMBL21394648 | 0.80 | SIRT2 (0.43) | SIRT2TMPRSS4F10CYP3A4DEGS1 | |
| SCHEMBL21394654 | 0.79 | WNT3A (0.44) | F10DEGS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21394650 | 0.78 | PARP1 (0.41) | F10DEGS1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21395122 | 0.77 | L3MBTL1 (0.43) | SIRT2TMPRSS4F10SMN1; SMN2NPC1 | |
| SCHEMBL29356885 | 0.77 | RAB9A (0.41) | SIRT2TMPRSS4F10CYP3A4SMN1; SMN2 | |
| SCHEMBL21395110 | 0.77 | RAB9A (0.41) | SIRT2TMPRSS4F10CYP3A4SMN1; SMN2 | |
| SCHEMBL21394952 | 0.74 | KCNQ3 (0.44) | SIRT2CYP3A4DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |