Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356767 | 0.92 | L3MBTL1 (0.47) | L3MBTL1TSHRHTTENPP2GRM5 | |
| SCHEMBL21394600 | 0.92 | L3MBTL1 (0.47) | L3MBTL1TSHRHTTENPP2GRM5 | |
| SCHEMBL21384407 | 0.84 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTGRM5MEN1 | |
| SCHEMBL29356947 | 0.84 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTGRM5MEN1 | |
| SCHEMBL29357829 | 0.82 | ALDH1A1 (0.40) | VNN1MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL21394769 | 0.82 | ALDH1A1 (0.40) | VNN1MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL29353756 | 0.82 | SMN1; SMN2 (0.41) | L3MBTL1TSHRVNN1MAPTALDH1A1 | |
| SCHEMBL21394511 | 0.82 | SMN1; SMN2 (0.41) | L3MBTL1TSHRVNN1MAPTALDH1A1 | |
| SCHEMBL21384174 | 0.82 | MET (0.44) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL29357023 | 0.82 | MET (0.44) | MEN1KMT2AMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |