Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357829 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MME | |
| SCHEMBL29353756 | 0.92 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MMEP2RY14RAB9A | |
| SCHEMBL21394511 | 0.92 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MMEP2RY14RAB9A | |
| SCHEMBL21394600 | 0.88 | L3MBTL1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL29356767 | 0.88 | L3MBTL1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL21394765 | 0.82 | L3MBTL1 (0.42) | ALDH1A1P2RY14RAB9ALMNATP53 | |
| SCHEMBL29356949 | 0.82 | ABCC8 (0.46) | ALDH1A1SMN1; SMN2P2RY14RAB9ANPC1 | |
| SCHEMBL21384455 | 0.82 | ABCC8 (0.46) | ALDH1A1SMN1; SMN2P2RY14RAB9ANPC1 | |
| SCHEMBL21394510 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19P2RY14 | |
| SCHEMBL29358244 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |