Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394934 | 0.83 | KDM4E (0.47) | RAB9AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL29356723 | 0.83 | ALDH1A1 (0.47) | RAB9AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL21394836 | 0.83 | ALDH1A1 (0.47) | RAB9AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL21395006 | 0.82 | MEN1 (0.52) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21394887 | 0.82 | MAPT (0.47) | RAB9AMAPTALDH1A1KDM4EHTT | |
| SCHEMBL29353798 | 0.81 | SCD (0.52) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL21394882 | 0.81 | SCD (0.52) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL21394922 | 0.81 | RAB9A (0.55) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL29357533 | 0.81 | RAB9A (0.55) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL21395166 | 0.79 | RAB9A (0.44) | RAB9AMAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |