Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394950 | 0.88 | CHEK1 (0.49) | — | |
| SCHEMBL21394713 | 0.87 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21394947 | 0.82 | JUN (0.43) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21395192 | 0.81 | L3MBTL1 (0.43) | RAB9ANPC1TP53CYP1A2CYP3A4 | |
| SCHEMBL21395032 | 0.81 | SMN1; SMN2 (0.42) | RAB9ANPC1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL29357852 | 0.78 | NPC1 (0.53) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL21394758 | 0.78 | NPC1 (0.53) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL21394842 | 0.77 | SMN1; SMN2 (0.44) | RAB9ANPC1TP53CYP1A2CYP3A4 | |
| SCHEMBL29356712 | 0.77 | SMN1; SMN2 (0.44) | RAB9ANPC1TP53CYP1A2CYP3A4 | |
| SCHEMBL21395025 | 0.77 | NPC1 (0.45) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |