Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394947 | 0.94 | JUN (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL21395031 | 0.89 | CHEK1 (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL21395002 | 0.86 | TMPRSS4 (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL21394713 | 0.86 | NPC1 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL21395154 | 0.84 | TMPRSS4 (0.44) | JUNNFKB1NFKB2RELACYP3A4 | |
| SCHEMBL21394932 | 0.81 | CHEK1 (0.42) | — | |
| SCHEMBL21394955 | 0.81 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1CYP3A4GRM5 | |
| SCHEMBL21394626 | 0.79 | L3MBTL1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL21394851 | 0.79 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL29357041 | 0.79 | L3MBTL1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |