Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394958 | 0.91 | P2RX3 (0.42) | P2RX3GCKDEGS1 | |
| SCHEMBL29358537 | 0.87 | GCK (0.41) | CYP3A4GCKDEGS1 | |
| SCHEMBL21395054 | 0.87 | GCK (0.41) | CYP3A4GCKDEGS1 | |
| SCHEMBL21394921 | 0.84 | NPC1 (0.48) | P2RX3 | |
| SCHEMBL21395179 | 0.83 | GCK (0.42) | CYP3A4SIRT2GCKDEGS1 | |
| SCHEMBL29357585 | 0.82 | ALDH1A1 (0.41) | SIRT2EP300 | |
| SCHEMBL21394628 | 0.82 | ALDH1A1 (0.41) | SIRT2EP300 | |
| SCHEMBL21394649 | 0.82 | P2RX3 (0.45) | P2RX3DEGS1 | |
| SCHEMBL21394875 | 0.81 | EP300 (0.42) | EP300 | |
| SCHEMBL29358580 | 0.81 | EP300 (0.42) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |