Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873030 | 0.78 | MAOB (0.64) | MAOBMAOA | |
| SCHEMBL17521499 | 0.77 | MAOA (0.54) | MAOBMAOACYP11B1CYP11B2CYP17A1 | |
| SCHEMBL21384192 | 0.76 | NFE2L2 (0.45) | MAOBCYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL29442828 | 0.76 | NFE2L2 (0.45) | MAOBCYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL21383952 | 0.76 | NOS1 (0.46) | MAOBCYP11B1CYP11B2TAAR1 | |
| SCHEMBL21394846 | 0.76 | TAAR1 (0.45) | MAOBCYP11B1CYP11B2CYP17A1CYP3A4 | |
| SCHEMBL9938749 | 0.75 | HCAR2 (0.57) | CYP11B1CYP11B2CYP3A4SNCAHCAR2 | |
| SCHEMBL29442799 | 0.75 | HCAR2 (0.57) | CYP11B1CYP11B2CYP3A4SNCAHCAR2 | |
| SCHEMBL2555787 | 0.74 | F2R (0.49) | CYP11B1CYP11B2CYP17A1CYP3A4TAAR1 | |
| SCHEMBL7929350 | 0.74 | TAAR1 (0.52) | MAOBCYP11B1CYP11B2CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |