Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755263 | 0.80 | GRM2 (0.42) | TAAR1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL29442828 | 0.80 | NFE2L2 (0.45) | TAAR1CYP11B1CYP11B2MAOBCYP3A4 | |
| SCHEMBL21395199 | 0.80 | TAAR1 (0.45) | TAAR1MAOBKDM4E | |
| SCHEMBL21384192 | 0.80 | NFE2L2 (0.45) | TAAR1CYP11B1CYP11B2MAOBCYP3A4 | |
| SCHEMBL21383952 | 0.80 | NOS1 (0.46) | TAAR1CYP11B1CYP11B2MAOBIDO1 | |
| SCHEMBL12885845 | 0.79 | KCNQ3 (0.43) | CYP11B1CYP11B2MAOBCYP17A1SMN1; SMN2 | |
| SCHEMBL1564270 | 0.78 | PLA2G7 (0.50) | CYP11B1CYP11B2CYP3A4SMN1; SMN2 | |
| SCHEMBL3300303 | 0.78 | TAAR1 (0.60) | TAAR1CYP11B1CYP11B2IDH1MAOB | |
| SCHEMBL22479639 | 0.78 | GPR52 (0.38) | CYP11B1CYP11B2KDM4EP2RX7SMN1; SMN2 | |
| SCHEMBL10487072 | 0.77 | PKM (0.51) | TAAR1CYP11B1CYP11B2CYP3A4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |