Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189663 | 1.00 | ENPP2 (0.33) | ENPP2CYP11B2CYP11B1 | |
| SCHEMBL30189704 | 0.84 | CCR1 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL19783287 | 0.84 | CCR1 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL30189933 | 0.79 | S1PR4 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL19783603 | 0.79 | S1PR4 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL19783099 | 0.74 | — | — | |
| SCHEMBL29277947 | 0.74 | HTR1A (0.39) | — | |
| SCHEMBL29939888 | 0.74 | HTR1A (0.39) | — | |
| SCHEMBL30189775 | 0.73 | KDM4E (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL19783559 | 0.73 | KDM4E (0.34) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | ENPP2 415/4885CYP11B2 367/4885CYP11B1 376/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | ENPP2 523/4885CYP11B2 245/4885CYP11B1 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.