SCHEMBL21396726

SCHEMBL21396726

N#Cc1ccc(N2c3ccccc3C3(c4ccccc4Oc4ccccc43)c3ccccc32)cc1-c1cc(N2c3ccccc3C3(c4ccccc4Oc4ccccc43)c3ccccc32)ccn1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.33
GRIA1 P42261 1/20 0.30
GRIA3 P42263 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21397129 0.90 GRIA1 (0.33) ARGRIA1GRIA3PDE4D
SCHEMBL21396738 0.89 AR (0.37) ARGRIA1GRIA3PDE4D
SCHEMBL21397200 0.84 AR (0.41) ARGRIA1GRIA3PDE4D
SCHEMBL21396728 0.83 AR (0.32) AR
SCHEMBL22147589 0.80 ALDH1A1 (0.33)
SCHEMBL22065077 0.78 USP30 (0.35)
SCHEMBL22065909 0.78 HCRTR1 (0.32)
SCHEMBL21397047 0.77 HDAC6 (0.35) ARGRIA1GRIA3PDE4D
SCHEMBL19344992 0.77 KDM4E (0.35) AR
SCHEMBL19344964 0.76 PGR (0.36) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLC18A1 AR 3741/4885GRIA1 2754/4885GRIA3 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.