Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.63 |
| ▸ | CA9 | Q16790 | 6/20 | 0.63 |
| ▸ | CA1 | P00915 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624040 | 0.81 | CA2 (0.68) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL561014 | 0.81 | CA2 (0.68) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL4602446 | 0.79 | CA2 (0.65) | CA2CA9CA1TSHRIDO1 | |
| Ammonia Solution, Strong SCHEMBL28824539 | 0.79 | CA2 (0.65) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL3070178 | 0.78 | CA2 (0.58) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL9869989 | 0.77 | CA2 (0.63) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL249386 | 0.77 | CA2 (0.63) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL14955045 | 0.77 | CA2 (0.63) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL1263515 | 0.77 | CA2 (0.63) | CA2CA9CA1TSHRIDO1 | |
| SCHEMBL332355 | 0.77 | CA2 (0.63) | CA2CA9CA1TSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911516-B1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION PROCESS | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8586498-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-8497400-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-30 | — | — | US | disclosed |
| US-8481791-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| EP-2392400-A2 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2011-12-07 | — | — | EP | disclosed |
| US-20110065929-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-7902110-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100137615-A1 | Homogeneous Asymmetric Hydrogenation Process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2095875-A1 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-1911516-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137615-A1 | Homogeneous Asymmetric Hydrogenation Process | HDHD5, HHAT, HVCN1 | CA2 2980/4885CA9 2420/4885CA1 2208/4885 |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | HDHD5, HHAT, HACL2 | CA2 2530/4885CA9 1991/4885CA1 1609/4885 |
| US-20110065929-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | HDHD5, HHAT, HACL2 | CA2 2530/4885CA9 1991/4885CA1 1609/4885 |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | HDHD5, HHAT, HVCN1 | CA2 2980/4885CA9 2420/4885CA1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.