SCHEMBL249386

SCHEMBL249386

CS(=O)(=O)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.63
CA9 Q16790 6/20 0.63
CA1 P00915 5/20 0.63
TSHR P16473 2/20 0.48
AR P10275 2/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 2/20 0.47
IDO1 P14902 1/20 0.44
CA5A P35218 2/20 0.43
AGXT P21549 1/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
FAAH O00519 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27447210 1.00 CA2 (0.63) CA2CA9CA1TSHRAR
Formaldehyde SCHEMBL28740532 0.96 CA2 (0.59) CA2CA9CA1TSHRAR
Ethyne SCHEMBL28196610 0.96 CA2 (0.59) CA2CA9CA1TSHRAR
SCHEMBL27571883 0.94 TSHR (0.60) CA2CA9CA1TSHRAR
SCHEMBL9502200 0.92 CA2 (0.55) CA2CA9CA1TSHRAR
SCHEMBL4952656 0.88 CA2 (0.58) CA2CA9CA1TSHRAR
SCHEMBL6286312 0.88 IDO1 (0.52) CA2CA9CA1TSHRIDO1
SCHEMBL874437 0.87 AR (0.62) CA2CA9CA1ARNPC1
SCHEMBL29264749 0.87 ALDH1A1 (0.50) CA2CA9CA1TSHRAR
SCHEMBL633239 0.86 CA2 (0.53) CA2CA9CA1TSHRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025254-A Preparation method of epothilone hydrochloride intermediate 甘肃皓天医药科技有限责任公司 2025-05-23 CN claimed
CN-117241773-A Polymer medicine bottle with standard external dimensions and reduced internal volume SIO2医疗产品有限公司 2023-12-15 CN claimed
CN-107056733-B 3-O-(with anticancer activity is to methanesulfonates benzyl) ascorbic acid and preparation method 中国药科大学 2019-09-03 CN claimed
CN-109369619-A Phthalazines ketone compound crystal form B and preparation method thereof 南京先进生物材料与过程装备研究院有限公司 2019-02-22 CN claimed
CN-109336864-A Phthalazines ketone compound crystal form N and preparation method thereof 南京先进生物材料与过程装备研究院有限公司 2019-02-15 CN claimed
CN-109288830-A A kind of taxol and novel phthalazines ketone compounds drug combination compositions 南京先进生物材料与过程装备研究院有限公司 2019-02-01 CN claimed
CN-109180644-A A kind of mesylate of novel B TK kinase inhibitor and preparation method thereof and purposes 南京先进生物材料与过程装备研究院有限公司 2019-01-11 CN claimed
CN-109180643-A Phthalazines ketone compound crystal form A and preparation method thereof 南京先进生物材料与过程装备研究院有限公司 2019-01-11 CN claimed
CN-109172592-A A kind of antineoplastic pharmaceutical compositions 南京先进生物材料与过程装备研究院有限公司 2019-01-11 CN claimed
CN-108218800-A 1,2,3- triazole aminopeptidase N inhibitor and its preparation method and application 山东大学 2018-06-29 CN claimed
CN-1662522-A Novel compounds, their use and preparation BIOVITRUM AB (SE) 2005-08-31 CN claimed
WO-2005076749-A2 A NOVEL PROCESS FOR THE PREPARATION OF 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE JUBILANT ORGANOSYS LIMITED (IN) 2005-08-25 WO claimed
EP-1513831-A1 NOVEL COMPOUNDS, THEIR USE AND PREPARATION Biovitrum AB (SE) 2005-03-16 EP claimed
US-20040029888-A1 Novel compounds, their use and preparation PROXIMAGEN NEUROSCIENCE PLC (GB) 2004-02-12 US claimed
WO-2004000830-A1 NOVEL COMPOUNDS, THEIR USE AND PREPARATION BIOVITRUM AB (SE) 2003-12-31 WO claimed
EP-0802904-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 1998-09-09 EP claimed
CN-1172477-A Substituted 2 -phenylpyridines as herbicides BASF AG (DE) 1998-02-04 CN claimed
EP-0079134-B1 STEREOSPECIFIC SYNTHESIS OF 5-PHENYL-2S-PENTANOL PFIZER INC. (US) 1985-02-06 EP claimed
US-4412958-A Stereospecific synthesis of 5-phenyl-2S-pentanol PFIZER INC. (US) 1983-11-01 US claimed
EP-0079134-A1 Stereospecific synthesis of 5-phenyl-2S-pentanol PFIZER INC. (US) 1983-05-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029888-A1 Novel compounds, their use and preparation TPH1, TPH2, HTR1A CA2 4669/4885CA9 4529/4885CA1 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.