Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378060 | 0.90 | ALDH1A1 (0.34) | PDE10AALDH1A1CYP2C19TSHRELANE | |
| SCHEMBL21378041 | 0.90 | PDE9A (0.35) | PDE10AAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21396835 | 0.90 | ALDH1A1 (0.37) | ALDH1A1CYP2C19TSHRNTRK1PIM1 | |
| SCHEMBL21397098 | 0.89 | PDE9A (0.40) | AKR1C4AKR1C3AKR1C2AKR1C1PDE9A | |
| SCHEMBL21396827 | 0.85 | ALDH1A1 (0.38) | ALDH1A1CYP2C19TSHRELANEUSP14 | |
| SCHEMBL21397113 | 0.85 | ALDH1A1 (0.37) | PDE10APDE9APDE1CALDH1A1CYP2C19 | |
| SCHEMBL21396598 | 0.85 | ALDH1A1 (0.37) | PDE10APDE9APDE1CALDH1A1CYP2C19 | |
| SCHEMBL21396826 | 0.85 | CYP11B2 (0.38) | PDE10AAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21377976 | 0.84 | ALDH1A1 (0.35) | ALDH1A1CYP2C19TSHRNTRK1PIM1 | |
| SCHEMBL19909047 | 0.83 | CYP11B2 (0.38) | PDE9APDE1CALDH1A1ELANECYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292181-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292181-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, SLCO1B3, NDUFV3 | PDE10A 3833/4885AKR1C4 3938/4885AKR1C3 3798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.