SCHEMBL21397151

SCHEMBL21397151

N#Cc1ccc(N2c3ccccc3Oc3ccccc32)cc1-c1ccc(N2c3ccccc3Oc3ccccc32)nc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.33
RET P07949 9/20 0.33
HDAC1 Q13547 2/20 0.33
NR3C1 P04150 1/20 0.32
CNR2 P34972 1/20 0.32
AR P10275 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396728 0.91 AR (0.32) GPR119RETHDAC1AR
SCHEMBL21396767 0.84 AR (0.40) GPR119RETHDAC1AR
SCHEMBL21397036 0.84 FNTA (0.36) GPR119RETHDAC1NR3C1CNR2
SCHEMBL19344992 0.83 KDM4E (0.35) ARALDH1A1LMNAHPGDMAPK1
SCHEMBL21396938 0.82 RET (0.35) RETHDAC1
SCHEMBL21397130 0.80 ALDH1A1 (0.35) CNR2ALDH1A1SMN1; SMN2EGLN1
SCHEMBL21397129 0.80 GRIA1 (0.33) ARALDH1A1LMNAHPGDMAPK1
SCHEMBL21397153 0.78 ABL1 (0.33) ALDH1A1EGLN1
SCHEMBL17883162 0.78 CNR1 (0.36) ALDH1A1LMNAHPGDMAPK1SMN1; SMN2
SCHEMBL19344940 0.77 PGR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLC18A1 GPR119 4589/4885RET 3927/4885HDAC1 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.