SCHEMBL17883162

SCHEMBL17883162

N#Cc1cc(-c2ccc(N3c4ccccc4Oc4ccccc43)cc2)c(C#N)cc1-c1ccc(N2c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.36
ESR2 Q92731 1/20 0.35
KDM4E B2RXH2 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
MAPKAPK2 P49137 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GALR3 O60755 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29512218 0.94 LMNA (0.35) CNR1ESR2KDM4ESMN1; SMN2NPSR1
SCHEMBL17483438 0.94 LMNA (0.35) CNR1ESR2KDM4ESMN1; SMN2NPSR1
SCHEMBL17955070 0.88 ESR2 (0.49) ESR2HSD17B10ALDH1A1HPGDCYP1A2
SCHEMBL19344940 0.88 PGR (0.36) ESR2PGR
SCHEMBL19345027 0.88 STS (0.42) ESR2PGR
SCHEMBL17955092 0.87 KDM4E (0.35) ESR2KDM4EHSD17B10ALDH1A1P2RX4
SCHEMBL17483336 0.86 ALDH1A1 (0.36) CNR1KDM4ESMN1; SMN2NPSR1MEN1
SCHEMBL19344959 0.85 KDM4E (0.35) KDM4ESMN1; SMN2MEN1MAPTKMT2A
SCHEMBL17850990 0.85
SCHEMBL21240043 0.84 PGR (0.35) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2021-03-02 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20200035922-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-01-30 US disclosed
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2019-11-14 US disclosed
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-08-13 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 CNR1 649/4885ESR2 1216/4885KDM4E 3804/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 CNR1 649/4885ESR2 1216/4885KDM4E 3804/4885
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND CRY2, NR2E3, CRY1 CNR1 1480/4885ESR2 87/4885KDM4E 3930/4885
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound CRY1, CRY2, GLB1 CNR1 541/4885ESR2 434/4885KDM4E 4226/4885
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound CRY2, NR2E3, CRY1 CNR1 1480/4885ESR2 87/4885KDM4E 3930/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA CNR1 1032/4885ESR2 697/4885KDM4E 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.