SCHEMBL21397945

SCHEMBL21397945

Cc1cc(-c2ccc(-c3ccccc3-c3cc(B4OC(C)(C)C(C)(C)O4)cc(-c4ccccc4-c4ccc(-c5cc(C)c(-c6cccc(-c7ccccc7)c6)cn5)cc4)c3)cc2)ncc1-c1cccc(-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 8/20 0.45
LPL P06858 7/20 0.45
DGAT1 O75907 1/20 0.41
PDGFRB P09619 2/20 0.38
KDR P35968 2/20 0.38
LDHA P00338 1/20 0.38
ENPP3 O14638 2/20 0.36
IRAK4 Q9NWZ3 2/20 0.35
ENPP1 P22413 1/20 0.32
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19933638 0.96 LIPG (0.46) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL20696474 0.93 LIPG (0.43) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL18015367 0.91 LIPG (0.56) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL20068707 0.91 LIPG (0.42) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL19794355 0.90 LIPG (0.43) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL19833340 0.88 LPL (0.45) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL18015329 0.86 LIPG (0.57) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL19933732 0.85 DGAT1 (0.38) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL19794357 0.85 LIPG (0.46) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL23018785 0.85 DGAT1 (0.39) LIPGLPLDGAT1PDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 US disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 LIPG 3438/4885LPL 3633/4885DGAT1 1147/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 LIPG 3438/4885LPL 3633/4885DGAT1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.