Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313813 | 0.82 | HSD11B1 (0.58) | HSD11B1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9221256 | 0.81 | HSD11B1 (0.46) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL12265806 | 0.81 | HSD11B1 (0.52) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL6667849 | 0.80 | HSD11B1 (0.51) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL21400324 | 0.79 | TRPM8 (0.57) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL14948977 | 0.78 | HSD11B1 (0.54) | HSD11B1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL9222169 | 0.76 | TRPM8 (0.42) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL7501656 | 0.76 | — | — | |
| SCHEMBL9473719 | 0.75 | HSD11B1 (0.47) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL21400320 | 0.75 | SLC6A2 (0.48) | HSD11B1KMT2AALDH1A1MAPTTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019179515-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |