Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19472466 | 0.81 | EGFR (0.50) | RAB9ANPC1KMT2AEGFRITK | |
| SCHEMBL21400129 | 0.80 | HSD11B1 (0.56) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL12313813 | 0.77 | HSD11B1 (0.58) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL491378 | 0.76 | NPC1 (0.65) | RAB9ANPC1KMT2AEGFRITK | |
| SCHEMBL12265806 | 0.75 | HSD11B1 (0.52) | HSD11B1RAB9ANPC1KMT2ATRPM8 | |
| SCHEMBL23227079 | 0.75 | ALDH1A1 (0.54) | RAB9ANPC1EGFRITK | |
| SCHEMBL19481325 | 0.75 | EGFR (0.46) | RAB9ANPC1KMT2AEGFRITK | |
| SCHEMBL4889217 | 0.75 | MTOR (0.50) | RAB9ANPC1EGFRITK | |
| SCHEMBL16257002 | 0.73 | BCL2A1 (0.56) | RAB9ANPC1KMT2AEGFRITK | |
| SCHEMBL14948977 | 0.73 | HSD11B1 (0.54) | HSD11B1RAB9ANPC1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226138-B1 | FAB I INHIBITORS | AFFINIUM PHARM INC (CA) | 2004-12-29 | — | — | EP | disclosed |